Polydimethylsiloxane (PDMS) belongs to a group of polymeric organosilicon compounds. Due to its versatility and rheological properties, PDMS is the most widely used silicon-based organic polymer. It is optically clear and, generally, inert, non-toxic, and non-flammable. The diversity of PDMS applications is extraordinary: from contact lenses and medical devices to elastomers, shampoos, food, caulking, lubricants, and heat-resistant tile.
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In science, PDMS is mostly utilized as a sample substrate in the Raman analysis of substances. Raman spectroscopy with PDMS-based microdevices allows to perform on-chip, droplet-based, in vivo biomolecular analysis with a single-cell resolution; monitor the process of investigating PDMS substrate effects on hydrogenation of graphene; etc. Even though the PDMS Raman scattering signal is extremely strong, this material is applied universally because of its outstanding properties, such as excellent gas permeability and optical transparency.
Raman spectroscopy can uniquely identify many chemical and biological agents.All substances