Polydimethylsiloxane (PDMS) belongs to a group of polymeric organosilicon compounds. Due to its versatility and rheological properties, PDMS is the most widely used silicon-based organic polymer. It is optically clear and, generally, inert, non-toxic, and non-flammable. The diversity of PDMS applications is extraordinary: from contact lenses and medical devices to elastomers, shampoos, food, caulking, lubricants, and heat-resistant tile.
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In science, PDMS is mostly utilized as a sample substrate in the Raman analysis of substances. Raman spectroscopy with PDMS-based microdevices allows to perform on-chip, droplet-based, in vivo biomolecular analysis with a single-cell resolution; monitor the process of investigating PDMS substrate effects on hydrogenation of graphene; etc. Even though the PDMS Raman scattering signal is extremely strong, this material is applied universally because of its outstanding properties, such as excellent gas permeability and optical transparency.